MD

Title

Chlamydia trachomatis and Abnormal Reproductive Function in the Female

The MD by thesis was a novel addition to the postgraduate degree courses offered at the University of the West Indies, and the award of this degree was a milestone since it was the very first amongst all Campuses at this University.

Details of Thesis

Supervisor

Professor Hugh Wynter, UWI, Mona Jamaica.

External Examiner

Dr. Joseph Jordan, Birmingham, England.

Theme

This was a study of the organism C. trachomatis which is becoming increasingly recognised to be the commonest sexually transmitted disease worldwide, even surpassing gonorrhoea, syphilis and HIV.  Long term consequences include ectopic pregnancy and possibly miscarriage.  Since the organism is difficult to identify, this work sought to locate Chlamydial DNA within infected tissues, such as the Fallopian tubes, the ovaries and the uterine lining (endometrium).

Together with research colleagues at the University of Sheffield, UK we accumulated (at that time) the largest database in the research community worldwide, for Chlamydial DNA in these tissues.

Number of pages

110

Presentations of thesis-generated work at International Scientific Meetings:

  • The prevalence of C. trachomatis in women with a history of miscarriage or ectopic pregnancy
    Abstract: 173rd Meeting of Pathological Society of Great Britain and Ireland. Southampton UK (1996)
  • The prevalence of C. trachomatis in women presenting with ectopic pregnancy in Trinidad
    Abstract: 3rd Meeting of European Society for Chlamydial Research,                     Vienna, Austria (1996)
  • Molecular Methods for defining the prevalence of C. trachomatis in gynaecological patients in Trinidad
    Abstract: Joint International Postgraduate Conference of the
    Gynaecological and Obstetrical Society of Trinidad and Tobago and
    The Royal College of Obstetricians and Gynaecologists, UK.
    Trinidad (1997)
  • The detection of C. trachomatis in women presenting with ectopic pregnancy or infertility
    Abstract: Meeting of Federation of European Microbiological Societies, Izmir, Turkey (1997)
  • Impaired female fertility: a role for C. trachomatis
    Abstract: 175th Meeting of Pathological Society of Great Britain and
    Ireland. Sheffield, UK (1997)
  • Molecular methods to detect C. trachomatis in patients with ectopic pregnancy
    Abstract: 176th Meeting of Pathological Society of Great Britain and
    Ireland. London, UK (1998)
  • The use of molecular methods to detect C. trachomatis in patients with ectopic pregnancy or tubal factor infertility
    Abstract: 9
    th International Symposium on Human Chlamydial Infection, Napa California, USA (1998)